How RAPTIVA Works

RAPTIVA: change your psoriasis for the better.

• "It's not a topical solution. It's not an ointment, it's not a cream. It's an injection that goes into the skin and attacks the psoriasis. That's what's different about RAPTIVA."*
• Angela, RAPTIVA patient, 3 months
• *Individual results may vary.

To understand how RAPTIVA works, you first need to understand how psoriasis works. In psoriasis, overactive T-cells tell your skin cells to multiply faster and faster. The result is the red, inflamed, or silvery, scaly build-up of skin called plaque psoriasis.

RAPTIVA is a biologic that targets and controls the cells that are creating the problem. RAPTIVA tells the T-cells to stop giving orders to your skin cells. And then your skin cells begin to multiply at a more normal rate, and your skin's shedding cycle becomes more normal, too. That's why many people who take RAPTIVA experience an improvement in their psoriasis symptoms.

Keep in mind, it can take some time for the T-cells to stop giving orders, and time for the skin cells to listen. If RAPTIVA works for you, you should see noticeable results in about 12 weeks. But everyone is different, so be patient.

With RAPTIVA, you could see real results.

In clinical trials, RAPTIVA has been shown to reduce the amount of skin area affected by psoriasis and the thickness, redness, and scaling of plaques. And after 12 weeks, a significant improvement was seen by nearly 60% of patients.

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• Actual patient who used RAPTIVA in clinical trials. Individual results may vary.

RAPTIVA is proven to work when you keep using it.

Like all other chronic conditions, to control your psoriasis you may need to use medicine long-term. This is the case with RAPTIVA. It is intended for long-term continuous use.

• "It's an ongoing thing. If it works for you, RAPTIVA will help you as long as you keep taking it. So I plan on taking RAPTIVA as long as I have psoriasis, and I don't see any end in sight for that."*
• Tim S, RAPTIVA patient, 7 months
• *Individual results may vary.

For most patients, RAPTIVA works and keeps on working. In fact, a study showed that people who continued taking RAPTIVA long-term were still maintaining results with their skin. They had less itching, redness, and plaques, and more normal-looking skin.

As with other medicines, RAPTIVA has some side effects. The most common side effects with RAPTIVA are flu-like symptoms, such as headache, chills, fever, nausea, and muscle aches. These symptoms are usually mild and they go away a few days after your first 2 injections. If you need help managing these symptoms, talk to your doctor.